بررسی اثرات ضدمیکروبی نانوذرات ترکیبی مس و آلومینیوم - اکسید روی و اثرات سینرژیستی با بیوسایدیهای مختلف بر علیه باسیلوس سرئوس

Background: The purpose of this study was to investigate the effect of copper and aluminum-zinc oxide nanoparticles and their synergistic effects with conventional biocides against Bacillus cereus. Methods: Synthesis of copper-zinc oxide, aluminum-zinc oxide nanoparticles performed via co- precipitation method and nanoparticle properties were investigated using FTIR, XRD and TEM. The antimicrobial effects of nanoparticles were determined by determination of the inhibition zone diameter and the synergistic effects of nanoparticles with other conventional biocides determined by the inhibitory concentration fraction index. Results: The diameter of the inhibition zone for zinc oxide nanoparticles, copper doped zinc oxide and aluminum doped zinc oxide were 16.5, 26 and 20 mm, respectively. Investigation of synergist effects with two common antimicrobial agents, including hydrogen peroxide and sodium hypochlorite, have shown that the doped nanoparticles have synergistic effects with these antimicrobial compounds. Conclusion: It can be concluded that the doping of copper and aluminum elements in the zinc oxide structure improves its antimicrobial effects. Also, conventional antimicrobial compounds (hydrogen peroxide and sodium hypochlorite) have synergistic effects with synthetic copper nanoparticles and aluminum oxide zinc.